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Tumor Microenvironment Network »  Principal Investigators »  Co-Principal Investigators & Directors »  Gabriele Bergers, PhD
Gabriele Bergers, PhD
Gabriele Bergers, PhD

Co-Principal Investigator and Leader of Project 1


Department of Neurological Surgery and Anatomy
Neill H. and Linda S. Brownstein Endowed Chair in Brain Tumor Research
Principal Investigator, Brain Tumor Research Center
Faculty Member, Biomedical Sciences Graduate Program

Contact Information:

Department of Neurological Surgery
1450 3rd St, HD210
San Francisco, CA 94158

Lab: (415) 476-0370
Fax: (415) 476-0388

Lab Website:


Co-Principal Investigator and Leader of Project 1 

Dr. Bergers, Professor in the Departments of Neurological Surgery and Anatomy, is a PI in the Brain Tumor Research Center (BTRC) and holds the Neill. H. and Linda S. Brownstein Chair in Brain Tumor Research at UCSF. She is an internationally recognized scientist who brings over 17 years of experience in the field of tumor angiogenesis and mouse models of carcinogenesis. Her laboratory has made seminal discoveries regarding both the interactions among tumor cells, the vasculature, and inflammatory cell constituents in regulating neovascularization and invasion in various transgenic and orthotopic mouse models of cancer and in revealing and understanding adaptation mechanisms of tumors during the course of antiangiogenic therapy. She began working on angiogenic and invasive properties in brain tumor mouse models 10 years ago when she joined the Department of Neurosurgery at UCSF. During this period, she actively collaborated with various investigators, including Dr. William Weiss, who is a Project leader on the present U54 grant proposal, resulting in several peer-reviewed publications. Currently, she is the PI on two NIH-sponsored R01s investigating a novel stem cell population with mesenchymal and epithelial characteristics in pancreatic tumors and studying of evasion to antiangiogenic therapy in various tumor types including glioblastoma. She has received numerous awards, including the prestigious Sidney Kimmel Award and Sandler Opportunity Award. Dr. Bergers has also actively participated in several organizations, committees, and study sections. She is on the Editorial board of Cancer Research and Science. In addition, she has been serving on the NIH Tumor Microenvironment Study Section since 2006 and became Chair in 2010. Moreover, she has served as an External Advisory Board member for various Universities and pharmaceutical companies including Amgen and Pfizer. She is a current EAB member for the CHLA/USC Childhood Brain Tumor Group in Los Angeles and the Max-Planck-Institute for Biomedicine (Vascular Biology focus) in Muenster, Germany.